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Monoamine oxidase and semicarbazide-sensitive amine oxidase activities in bovine eye

  • A. Fernandez de Arriba
  • D. Balsa
  • K. F. Tipton
  • M. Unzeta
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 32)

Summary

The activities of MAO-A, MAO-B and the semicarbazide-sensitive amine oxidase (SSAO) were determined in bovine lens, retina, optic nerve, iris and epithelium. No activities were detected in lens but the SSAO activity was found to be rather evenly distributed in the other tissues. The SSAO activities determined with 1 μM benzylamine were about half those determined for MAO-B. MAO-A activity, measured with 5-HT as substrate, was considerably greater than those of MAO-B and SSAO, determined with 2-phenylethylamine and benzylamine, respectively, in all the eye tissues.

Keywords

Optic Nerve Monoamine Oxidase Amine Oxidase Phenyl Ethylamine Monoamine Oxidase Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Barrand MA, Callingham BA (1982) Monoamine oxidase activities in brown and adipose tissue of the rat: some properties and subcellular distribution. Biochem Pharmacol 31:2177–2184.PubMedCrossRefGoogle Scholar
  2. Callingham BA, Barrand MA (1987) Some properties of semicarbazide-sensitive amine oxidase. J Neural Transm [Suppl] 23:37–54.Google Scholar
  3. Fowler CJ, Oreland L, Marcusson J, Winblad B (1980) Titration of human brain monoamine oxidase-A and-B by clorgyline and L-deprenyl. Naunyn-Schmiedebergs Arch Pharmacol 311:263–272.PubMedCrossRefGoogle Scholar
  4. Precious E, Gunn CE, Lyles GA (1988) Deamination of methylamine by semicarbazide-sensitive amine oxidase in human umbilical artery and rat aorta. Biochem Pharmacol 37:707–713.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • A. Fernandez de Arriba
    • 1
  • D. Balsa
    • 1
  • K. F. Tipton
    • 1
  • M. Unzeta
    • 1
  1. 1.Departament de Bioquimica i Biologia Molecular, Facultat de MedicinaUniversitat Autonoma de BarcelonaBellaterra (Barcelona)Spain

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