Monoamine oxidase activity in blood platelets of migraine patients

  • Maria Margarida Caramona
  • M. D. Cotrim
  • C. Fontes Ribeiro
  • T. Macedo
Conference paper
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 32)


Biochemical changes in platelets of migraine patients during the attacks have been reported before, however there are some conflicting results. In an attempt to define the biochemical lesion in the platelets, we have carried out a survey of platelets monoamine oxidase in migraine patients with and without aura. Platelet MAO activity in platelets from migraine patients was significantly reduced when compared with normal platelets.


Monoamine Oxidase Migraine Patient Blood Platelet Monoamine Oxidase Activity Biochemical Lesion 
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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • Maria Margarida Caramona
    • 1
  • M. D. Cotrim
    • 1
  • C. Fontes Ribeiro
    • 2
  • T. Macedo
    • 2
  1. 1.Laboratório de FarmacologiaFaculdade de Farmácia da Universidade de Coimbra, Largo de D. DinisCoimbraPortugal
  2. 2.Instituto de Farmacologia e Terapêutica ExperimentalFaculdade de MedicinaCoimbraPortugal

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