• Georg Emil Cold
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 49)


During the last decade several studies of cerebral blood flow (CBF) and metabolism in the acute phase of head injury have been published. It is the aim of this review to describe the dynamic changes in CBF, cerebral metabolic rate of oxygen (CMRO2), cerebral autoregulation (CA), and reactivity to PaCO2 and barbiturate (metabolic reactivity) in the acute phase after severe head injury and to discuss the therapeutical consequences with reference to prolonged artificial hyperventilation, hypothermia, barbiturate sedation, and mannitol therapy.


Cerebral Blood Flow Head Injury Intracranial Hypertension Cerebral Autoregulation Severe Head Injury 
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Copyright information

© Springer-Verlag/Wien 1990

Authors and Affiliations

  • Georg Emil Cold
    • 1
  1. 1.Department of NeuroanesthesiologyÅrthus KommunehospitalÅrhusDenmark

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