Experimental Studies of Head Injury
The dynamic pathophysiological changes which follow head injury are caused by successive events. First, the trauma directly influences the cerebral circulation and metabolism. Later, the effect of mass-lesions caused by haematoma, ischaemia, brain oedema, intracranial hypertension, and systemic hypotension and hypertension may influence ICP, CBF, and CMRO2. Accordingly, studies in experimental models, including one or more of these pathogenic factors, are important in the understanding of the dynamic changes following head injury.
KeywordsHead Injury Cerebral Oedema Intracranial Hypertension Brain Energy Metabolism Sagital Motion
Unable to display preview. Download preview PDF.