Skip to main content

Electrophysiological methods in the early diagnosis of Parkinson’s disease

  • Chapter
Early Markers in Parkinson’s and Alzheimer’s Diseases

Part of the book series: New Vistas in Drug Research ((DRUG RESEARCH,volume 1))

Summary

Electrophysiological methods and motor performance tests are shown to be helpful to the early diagnosis of Parkinson’s disease. The most sensitive out of five motor tests studied here is visuo-manual tracking. Tremor recordings allow to differentiate between physiological and pathological tremor. An enhancement of long-latency reflexes may precede the development of parkinsonian symptoms on the hitherto unaffected side in unilateral parkinsonism. The combination of motor function tests with tremor and long-latency reflex recordings is likely to be more sensitive than any single test.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Benecke R, Rothwell JC, Dick JPR, Day BL, Marsden CD (1986) Performance of simultaneous movements in patients with Parkinson’s disease. Brain 109: 739–757

    Article  PubMed  Google Scholar 

  • Day BL, Dick JPR, Marsden CD (1984) Patients with Parkinson’s disease can employ a predictive motor strategy. J Neurol Neurosurg Psychiatry 47: 1299–1306

    Article  PubMed  CAS  Google Scholar 

  • Deuschl G, Lucking CH (1989) Tremor and electrically elicited long-latency reflexes in early stages of Parkinson’s disease. In: Przuntek H, Riederer P (eds) Early diagnosis and preventive therapy in Parkinson’s disease. Springer, Wien New York, p 103–110

    Google Scholar 

  • Deuschl G, Schenck E, Lucking CH (1985) Long-latency responses in human thenar muscles mediated by fast conducting muscle and cutaneous afferents. Neurosci Lett 55: 361–366

    Article  PubMed  CAS  Google Scholar 

  • Evarts EV, Teräiväinen H, Caine DB (1981) Reaction time in Parkinson’s disease. Brain 104: 167–186

    Article  PubMed  CAS  Google Scholar 

  • Flowers K (1978) Lack of prediction in the motor behaviour of parkinsonism. Brain 101: 35–52

    Article  PubMed  CAS  Google Scholar 

  • Goldenberg G, Wimmer A, Auff E, Schnaberth G (1986) Impairment of motor planning in patients with Parkinson’s disease: evidence from ideomotor apraxia testing. J Neurol Neurosurg Psychiatry 49: 1266–1272

    Article  PubMed  CAS  Google Scholar 

  • Hallett M (1985) Quantitative assessment of motor deficiency in Parkinson’s disease: ballistic movements. In: Delwaide PJ, Agnoli A (eds) Clinical neurophysiology in Parkinsonism. Elsevier, Amsterdam, p 351

    Google Scholar 

  • Hömberg V, Hefter H, Reiners K, Freund HJ (1987) Differential effects of changes in mechanical limb properties on pyhsiological and pathological tremor. J Neurol Neurosurg Psychiatry 50: 568–579

    Article  PubMed  Google Scholar 

  • Kraus PH, Przuntek H (1988) Motor performance test. In: Przuntek H, Riederer P (eds) Early diagnosis and preventive therapy in Parkinson’s disease. Springer, Wien New York, pp 75–82

    Google Scholar 

  • Lücking CH, Deuschl G, Strahl K, Schenck E (1986) Tremor im Früh-and Spätstadium der Parkinson-Krankheit. In: Fischer PA (Hrsg) Spätsyndrome der Parkinson-Krankheit. Editions Roche, Basel, S 99–113

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag/Wien

About this chapter

Cite this chapter

Lücking, C.H., Hufschmidt, A., Deuschl, G. (1990). Electrophysiological methods in the early diagnosis of Parkinson’s disease. In: Dostert, P., Riederer, P., Strolin Benedetti, M., Roncucci, R. (eds) Early Markers in Parkinson’s and Alzheimer’s Diseases. New Vistas in Drug Research, vol 1. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9098-2_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-9098-2_7

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9100-2

  • Online ISBN: 978-3-7091-9098-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics