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Contribution of motor performance tests to the early diagnosis of Parkinson’s disease

  • P. H. Kraus
  • P. Klotz
  • R. Steinberg
  • H. Przuntek
Part of the New Vistas in Drug Research book series (DRUG RESEARCH, volume 1)

Summary

With the help of multivariate statistical methods, we analysed the results of a motor performance test series consisting of simple subtests. We were able to differentiate almost completely between parkinsonian patients (most of whom showed only slight or very slight clinical symptoms) and age-matched controls: we found only 2% false negative diagnoses and no false positives. Thus, impairment of fine motor skills is very frequent in the early stages of the disease and standardized motor performance tests can contribute to its detection. Since we established that a deterioration of the test results is highly age-correlated for these patients, we expect that follow-up testing will further contribute to improve selectivity.

Keywords

Fine Motor Skill False Negative Diagnosis Ability Profile Motor Deficiency Motor Performance Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Duvoisin RC (1971) The evaluation of extrapyramidal disease. In: Ajuriaguerra J (ed) Monoamines, noyaux gris centraux et syndrome de Parkinson, Symposium Genève 1970. Masson, Paris, pp 313–325Google Scholar
  2. Evarts EV, Teräväinen H, Calne DB (1981) Reaction time in Parkinson’s disease. Brain 104: 167–186PubMedCrossRefGoogle Scholar
  3. Flowers KA (1975) Ballistic and corrective movements on an aiming task: intention tremor and Parkinsonian movement disorders compared. Neurology 25: 413–421PubMedGoogle Scholar
  4. Kraus PH, Przuntek H (1989) Motor performance test. In: Przuntek H, Riederer P (eds) Kraus PH, Przuntek H, pp 75–82 ( Key Topics in Bra in Research)Google Scholar
  5. Kraus PH, Klotz P, Fischer A, Przuntek H (1987 a) Assessment of symptoms of Parkinson’s disease by apparative methods. J Neural Transm [Suppl 25]: 89–96Google Scholar
  6. Kraus PH, Keck B, Klotz P, Przuntek H (1987 b) Computer aided analysis of diadochokinesia. Electroencephalogr Clin Neurophysiol 66 (5): 57Google Scholar
  7. Schoppe KJ (1974) Das MLS-Gerät: Ein neuer Testapparat zur Messung feinmotorischer Leistungen. Diagnostica 20: 43–46Google Scholar
  8. Webster DD (1968) Clinical analysis of the disability in Parkinson’s disease. Modern Treatment, Hagerstown (Md) 5: 257–282Google Scholar

Copyright information

© Springer-Verlag/Wien 1990

Authors and Affiliations

  • P. H. Kraus
    • 1
  • P. Klotz
    • 2
  • R. Steinberg
    • 1
  • H. Przuntek
    • 1
  1. 1.Department of Neurology, St. Josef HospitalUniversity of BochumFederal Republic of Germany
  2. 2.Department of NeurologyUniversity of WürzburgFederal Republic of Germany

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