Summary
Psychoanalysts in the first half of this century have speculated on the pathogenetic role of premorbid suppression of impulse in an introverted personality for later development of Parkinson’s disease. More recent studies seem to support introversion, a predisposition towards depression and mental inflexibility as frequent premorbid personality features of parkinsonians. Neurobehavioural abnormalities found in the early stages of the disease include set-shifting difficulties, cognitive slowing and depression. Premorbid behavioural traits might represent the earliest sign of brain neurochemical dysfunction in Parkinson’s disease.
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Poewe, W. (1990). The premorbid personality of patients with Parkinson’s disease. In: Dostert, P., Riederer, P., Strolin Benedetti, M., Roncucci, R. (eds) Early Markers in Parkinson’s and Alzheimer’s Diseases. New Vistas in Drug Research, vol 1. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9098-2_4
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DOI: https://doi.org/10.1007/978-3-7091-9098-2_4
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