Sandfly fever in Central Asia and Afghanistan

  • Sophia Ya. Gaidamovich
  • Natalia V. Khutoretskaya
  • Y. V. Asyamov
  • V. I. Tsyupa
  • Eugenia E. Melnikova
Part of the Archives of Virology Supplementum book series (ARCHIVES SUPPL, volume 1)


Sandfly fevers are caused by viruses of the family Bunyaviridae, genus Phlebovirus. Three strains of sandfly fever Naples (SFN) virus (Af-1008, Af-1038 and Af-130) and 2 strains of sandfly fever Sicilian (SFS) virus (Af-1028 and Af-83) were isolated from febrile Soviet servicemen in Afghanistan in May-August, 1986–1987. The new strains of SFN virus were slightly different antigenically from the original Sabin strain but clearly different from prototype Toscana virus. Forty paired serum samples from patients ill in 1986 and 64 paired serum samples from patients ill in 1987 were tested by neutralization and immunofluorescence. A fourfold or greater rise in antibody to SFN or SFS virus was observed in 87 subjects; 16 others had antibody to both viruses but a rise in titer to only one of them. In addition, 101 serum samples with or without antibody to these viruses were tested by immunofluorescence for antibodies to Toscana and Rift Valley fever viruses; none were positive.


Rift Valley Fever Virus Complement Fixation Rift Valley Fever Rift Valley Fever Virus 
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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • Sophia Ya. Gaidamovich
    • 1
    • 2
  • Natalia V. Khutoretskaya
    • 1
  • Y. V. Asyamov
    • 1
  • V. I. Tsyupa
    • 1
  • Eugenia E. Melnikova
    • 1
  1. 1.D.I. Ivanovsky Institute of VirologyU.S.S.R. Academy of Medical ScienceMoscowUSSR
  2. 2.D.I. Ivanovsky Institute of VirologyAcademy of Medical Sciences of the U.S.S.R.MoscowUSSR

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