Advertisement

Geographical distribution of hemorrhagic fever with renal syndrome and hantaviruses

  • H. W. Lee
  • P. W. Lee
  • L. J. Baek
  • Y. K. Chu
Part of the Archives of Virology Supplementum book series (ARCHIVES SUPPL, volume 1)

Summary

World-wide, about 150,000 people are hospitalized with hemorrhagic fever with renal syndrome (HFRS) (3–10% fatality) each year. The etiologic agents of HFRS are Hantaan, Seoul, and Puumala viruses of the genus Hantavirus, family Bunyaviridae. A severe form of HFRS, caused by Hantaan virus, occurs in Asia and eastern parts of Europe, a moderate form, caused by Seoul virus, occurs in Asia, and a mild form, caused by Puumala virus, occurs in Europe. Hantaan virus occurs in Asia and in eastern parts of Europe, Seoul-like viruses occur world-wide, Puumala virus occurs in Europe, and Prospect Hill and Leaky viruses (other hantaviruses) have been isolated in the U.S.A. The reservoirs of hantaviruses are rodents and other small mammals. Serologic studies of 42 hantaviruses isolated from HFRS patients and from animals indicated that there are 6 or 7 serotypes. In the 1990s, it is highly possible to identify HFRS and HFRS-like illnesses caused by hantaviruses in parts of the world where HFRS is not known because of the availability of serodiagnostic tests.

Keywords

Hemorrhagic Fever With Renal Syndrome Nephropathia Epidemica Hantaan Virus Puumala Virus Indirect Immunofluorescent Antibody 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Back LJ, Yanagihara R, Gibbs CJ, Miyazaki M, Gajdusek DC (1988) Leaky virus, a new hantavirus isolated from Mus musculus in the United States. J Gen Virol 69: 3129–3132CrossRefGoogle Scholar
  2. 2.
    Couland X, Chonaib E, Georges AJ (1987) First human case of hemorrhagic fever with renal syndrome in the Central African Republic. Trans R Soc Trop Med Hyg 81: 686CrossRefGoogle Scholar
  3. 3.
    Gavrilovskaya IN, Apekina NS, Miasnikov YA (1983) Features of circulation of hemorrhagic fever with renal syndrome virus among small mammals in the European USSR. Arch Virol 75: 313–316PubMedCrossRefGoogle Scholar
  4. 4.
    Hemorrhagic fever with renal syndrome: memorandum from a WHO meeting (1982) Bull WHO 61: 269–275Google Scholar
  5. 5.
    Karabatsos N (ed) (1985) International catalogue of arboviruses including certain other viruses of vertebrates, 3rd edn. American Society of Tropical Medicine and Hygiene, San Antonio, TexasGoogle Scholar
  6. 6.
    Lee HW (1988) Global update on distribution of hemorrhagic fever with renal syndrome and hantaviruses. Virus Info Exch Newslett 5: 82–84Google Scholar
  7. 7.
    Lee HW, Lee PW (1976) Korean hemorrhagic fever. I. Demonstration of causative antigen and antibodies. Kor J Intern Med 19: 371–394Google Scholar
  8. 8.
    Lee HW, Lee PW, Johnson KM (1978) Isolation of the etiologic agent of Korean hemorrhagic fever. J Infect Dis 137: 298–308PubMedCrossRefGoogle Scholar
  9. 9.
    Lee HW, van der Groen G (1989) Hemorrhagic fever with renal syndrome. Prog Med Virol 36: 62–102PubMedGoogle Scholar
  10. 10.
    Lee PW, Gibbs CJ, Gajdusek CJ, Yanagihar R (1985) Serotypic classification of hantaviruses by indirect immunofluorescent antibody and plaque reduction neutralization tests. J Clin Microbiol 22: 940–944PubMedGoogle Scholar
  11. 11.
    Lee PW, Meegan JM, LeDuc JW, Tkachenko EA, Tvanov AP, Rezapkin GV, Drozdov SG, Kitamura T, Tsai TF, Dalrymple JM (1989) Serologic techniques for detection of Hantaan virus infection, related antigens and antibodies. In: Lee HW, Dalrymple JD (eds) Manual of hemorrhagic fever with renal syndrome. WHO Collaborating Center for Virus Reference and Research (HFRS), Institute for Viral Diseases, Korea University, Seoul, pp 75–106Google Scholar
  12. 12.
    Schmaljohn CS, Hasty SE, Dalrymple JM, LeDuc JW, Lee HW, von Bornsdorff CH, Brummer-Korvenkontio M, Vaheri A, Tsai TF, Goldgaber D, Lee PW (1985) Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome. Science 227: 1041–1044PubMedCrossRefGoogle Scholar
  13. 13.
    Tkachenko EA, Tvanov AP, Gonets MA (1983) Potential reservoir and vectors of hemorrhagic fever with renal syndrome in the USSR. Ann Soc Belg Med Trop 63: 267–269PubMedGoogle Scholar
  14. 14.
    van der Groen G, Leirs H, Verhagen R (1986) Polyhostal nature of Hantaan virus. In: Proceedings Second Symposium Recent Advances in Rodent Control, Kuwait, pp 197–207Google Scholar
  15. 15.
    Wah LT, Mangalam S, Lee HW (1987) Hemorrhagic fever with renal syndrome. Report on a case in Malaysia. J Infect Dis 156: 1035–1036CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • H. W. Lee
    • 1
    • 2
  • P. W. Lee
    • 1
  • L. J. Baek
    • 1
  • Y. K. Chu
    • 1
  1. 1.WHO Collaborating Center for Virus Reference and Research (hemorrhagic fever with renal syndrome), Institute for Viral DiseasesKorea UniversitySeoulKorea
  2. 2.WHO Collaborating Center for Virus Reference and Research (hemorrhagic fever with renal syndrome), Institute for Viral DiseasesKorea UniversitySeoulKorea

Personalised recommendations