Summary
Thirty-three cases of hemorrhagic fever with renal syndrome (HFRS) have been serologically confirmed in Slovenia during the last five years. The clinical picture varied from mild to severe, with a mortality rate of 3%. Serum samples from 240 patients suspected of having HFRS were tested by immunofluorescence using four different hantaviral antigens. Three reactivity patterns were observed. Using capture enzyme immunoassay, IgM was detected in 100% acute-phase serum samples of patients. The distribution of hantaviral infections in small mammals was examined in two natural foci of HFRS. Two hantaviruses were found in these mammals. In one area, Clethrionomys glareolus was the predominant species, and most of their sera reacted to highest titer with Puumala virus; mild illness was diagnosed in this area. In the second location, Apodemus flavicollis predominated, and most of their sera reacted to highest titer with Hantaan virus; severe illness was diagnosed in this area.
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Avšič-Županc, T. et al. (1990). Evidence of the presence of two hantaviruses in Slovenia, Yugoslavia. In: Calisher, C.H. (eds) Hemorrhagic Fever with Renal Syndrome, Tick- and Mosquito-Borne Viruses. Archives of Virology Supplementum, vol 1. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9091-3_11
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DOI: https://doi.org/10.1007/978-3-7091-9091-3_11
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