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Kombinationstherapie mit Neuroleptika und Carbamazepin. Eine kontrollierte Studie

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Schizophrene erkennen, verstehen, behandeln

Part of the book series: Aktuelle Probleme der Schizophrenie ((SCHIZOPHRENIE,volume 1))

Zusammenfassung

In einer kontrollierten Studie an Patienten mit akuter Schizophrenie wurde die klinische Wirksamkeit der Neuroleptika Haldol und Clozapin über 35 Tage geprüft. Nach fünf Tagen Behandlungsdauer wurde bei jenen Patienten, bei denen keine Besserung des psychotischen Zustandsbildes auftrat, Carbamazepin in einer Dosierung von 600 mg täglich zugesetzt. In der statistischen Auswertung der Ergebnisse zeigte sich, daß die Kombinationstherapie mit Carbamazepin die klinische Wirksamkeit eines Standardneuroleptikums nicht entscheidend verbessern kann.

Summary

Combined treatment with neuroleptics and carbamazepin. A controlled study. The clinical efficacy of the neuroleptics Haldol and Clozapine was studied in patients with acute schizophrenia, in a controlled trial lasting 35 days. Patients, whose psychotic state failed to show improvement after treatment for five days, received in addition 600 mg carbamazepine daily. Statistical analysis of the results showed that combination with carbamazepine does not improve the clinical efficacy of a standard neuroleptic to any marked extent.

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Authors and Affiliations

  1. Landes-Nervenkrankenhaus Hall, A-6060, Hall in Tirol, Österreich

    Dr. M. Mair, I. Tschapeller & H. Schubert

Authors
  1. Dr. M. Mair
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  2. I. Tschapeller
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  3. H. Schubert
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Editor information

Editors and Affiliations

  1. Wien, Austria

    G. Schönbeck

  2. Klagenfurt, Austria

    T. Platz

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© 1990 Springer-Verlag/Wien

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Mair, M., Tschapeller, I., Schubert, H. (1990). Kombinationstherapie mit Neuroleptika und Carbamazepin. Eine kontrollierte Studie. In: Schönbeck, G., Platz, T. (eds) Schizophrene erkennen, verstehen, behandeln. Aktuelle Probleme der Schizophrenie, vol 1. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9089-0_7

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  • DOI: https://doi.org/10.1007/978-3-7091-9089-0_7

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-82208-1

  • Online ISBN: 978-3-7091-9089-0

  • eBook Packages: Springer Book Archive

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