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The Vascular Supply of the Hypothalamus-Pituitary Axis

  • J. Lobo Antunes
  • K. Muraszko
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 47)

Abstract

In 1930 Popa and Fielding described in the rat a specialized network of blood vessels, the hypothalamohypophyseal portal system, that connected the infundibulum (median eminence) and the sinusoids of the pars distalis of the pituitary gland. Its functional importance was not immediately understood. They found no venous drainage from the pituitary gland so they assumed that blood ran from the gland into the brain.

Keywords

Pituitary Gland Cavernous Sinus Median Eminence Pituitary Stalk Portal Vessel 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Adams JH, Daniel PM, Prichard MML (1963) Volume of the infarct in the anterior lobe of the monkey’s pituitary gland shortly after stalk section. Nature 198: 1205–1206PubMedCrossRefGoogle Scholar
  2. Antunes JL (1979) Neural control of reproduction. Neurosurgery 5: 63–70PubMedCrossRefGoogle Scholar
  3. Antunes JL, Louis K, Cogen P, Zimmerman EA, Ferin M (1980) Section of the pituitary stalk in the rhesus monkey: II. Morphological studies. Neuroendocrinology 30: 76–82PubMedCrossRefGoogle Scholar
  4. Antunes JL, Murasko K, Stark R, Chen R (1983) Pituitary blood flow in primates: a Doppler study. Neurosurgery 12: 492–495PubMedCrossRefGoogle Scholar
  5. Bergland RM, Davis SL, Page RB (1977) Pituitary secretes to brain (experiment in sheep) Lancet 2: 276–278PubMedCrossRefGoogle Scholar
  6. Bergland RM, Page RB (1978) Can the pituitary secrete directly to the brain? ( Affirmative anatomical evidence ). Endocrinology 102: 1325–1338PubMedCrossRefGoogle Scholar
  7. Dandy WE, Goetsch E (1911) The blood supply of the pituitary body. Am J Anat 11: 137–150CrossRefGoogle Scholar
  8. Daniel PM, Prichard MML (1975) Studies of the hypothalamus and the pituitary gland. Acta Endocrinol 80 [suppl]Google Scholar
  9. David MA, Csernay L, Laszlo FA, Kovacs K (1985) Hypophyseal blood flow in rats after destruction of the pituitary stalk. Endocrinology 77: 183–187CrossRefGoogle Scholar
  10. Goldman H, Sapirstein LA (1958) Determination of blood flow to the rat pituitary gland. Am J Physiol 194: 433–435PubMedGoogle Scholar
  11. Gorczyca W, Hardy J (1987) Arterial supply of the human anterior pituitary gland. Neurosurgery 20: 369–377PubMedCrossRefGoogle Scholar
  12. Green JD, Harris GW (1947) The neurovascular link between the neurohypophysis and adenohypophysis. J Endocrinol 5: 136–146PubMedCrossRefGoogle Scholar
  13. Houssay BA, Biasotti A, Sammartino R (1935) Modifications fonctionnelles de l’hypophyse après lésions infundibulo-tubériennes chez le crapaud. C R Soc Biol (Paris) 120: 725–727Google Scholar
  14. Kemeny AA, Jakubowski JA, Jefferson AA, Pasztor E (1985a) Blood flow and autoregulation in rat pituitary gland. J Neurosurg 63: 116–119PubMedCrossRefGoogle Scholar
  15. Kemeny AA, Jakubowski JA, Pasztor E, Jefferson AA, Wojcikiewicz R (1985b) Reduction of blood flow in the adenohypophysis of rats by bromocriptine. J Neurosurg 63: 120–124PubMedCrossRefGoogle Scholar
  16. Lees PD, Pickard JD (1987) Hyperprolactinaemia, intrasellar pituitary tissue pressure, and the pituitary stalk compression syndrome. J Neurosurg 67: 192–196PubMedCrossRefGoogle Scholar
  17. Lees PD, Richards HK, Pickard JD (1988) Changes in perfusion characteristics and blood flow in pituitary tumours. Adv Bio Sci 69: 457–460Google Scholar
  18. Lichardus B, Albrecht I, Ponec J, Linhart L (1977) Water deprivation for 24 hours increases selectively blood flow in the posterior pituitary of conscious rats. Endocrinol Exp 11: 99–104PubMedGoogle Scholar
  19. Morato MJX (1939) The blood supply of the hypophysis. Anat Rec 74: 297–320CrossRefGoogle Scholar
  20. Muraszko K, Chen RYZ, Antunes JL: To be publishedGoogle Scholar
  21. Page RB (1982) Pituitary blood flow. Am J Physiol 243: E427–442PubMedGoogle Scholar
  22. Page RB (1982) In vivo recording of the direction of pituitary blood flow. Presented at the 64th Annual Meeting of the Endocrine SocietyGoogle Scholar
  23. Page RB, Funsch DJ, Brennan RW, Hernandez MJ (1981) Regional neurohypophyseal blood flow and its control in adult sheep. Am J Physiol 241: R36–43PubMedGoogle Scholar
  24. Popa G, Fielding V (1930) A portal circulation from the pituitary to the hypothalamic region. J Anat 65: 88–91PubMedGoogle Scholar
  25. Porter JC, Dhariwal APS, McCann SM (1967) Quantitative evaluation of local blood flow of the adenohypophysis in rats. Endocrinology 80: 583–598PubMedCrossRefGoogle Scholar
  26. Scharrer E, Scharrer B (1940) Secretory cells within the hypothalamus. Res Publ Assoc Res Nery Ment Dis 20: 170–174Google Scholar
  27. Wislocki GB, King LS (1936) The permeability of the hypophysis and hypothalamus to vital dyes, with a study of the hypophyseal vascular supply. Am J Anat 58: 421–472CrossRefGoogle Scholar
  28. Worthington WC Jr (1955) Some observations on the hypophyseal portal system in the living mouse. Bull Johns Hopkins Hosp 97: 343–357PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • J. Lobo Antunes
    • 1
  • K. Muraszko
    • 2
  1. 1.Department of NeurosurgeryUniversity of Lisbon, Hospital de Santa MariaLisbonPortugal
  2. 2.Department of NeurosurgeryThe Neurological Institute of New YorkNew YorkUSA

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