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Neurotransmitter Actions and Interactions pp 13–28Cite as

The psychopharmacology of GABA synapses: update 1989

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Part of the book series: Journal of Neural Transmission ((NEURAL SUPPL,volume 29))

Summary

Recent advances in the psychopharmacology of GABA synapses are reviewed. The usefulness of GABA mimetics in tardive dyskinesia and epilepsy has been confirmed, as has a dysfunction of GABA synapses in the etiopathology of these conditions. The antidepressant profile of GABA agonists in animal models for depression has been extended. The role of GABA receptors in the mechanism of action of antidepressants has been further delineated, with a parallelism occurring between the behavioral and biochemical response to antidepressant drug treatment in different animal models of depression.

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Authors and Affiliations

  1. Synthélabo Recherche (L.E.R.S.), Paris, France

    Dr. K. G. Lloyd, P. Pichat, B. Scatton, B. Zivkovic, P. L. Morselli & G. Bartholini

  2. Synthélabo Recherche (L.E.R.S.), 58 rue de la Glacière, 75013, Paris, France

    Dr. K. G. Lloyd

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  1. Dr. K. G. Lloyd
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  2. P. Pichat
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  3. B. Scatton
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  4. B. Zivkovic
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  5. P. L. Morselli
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  6. G. Bartholini
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Editors and Affiliations

  1. Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel

    Moussa B. H. Youdim

  2. Biochemistry Department, Trinity College, Dublin, Ireland

    Keith F. Tipton

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Lloyd, K.G., Pichat, P., Scatton, B., Zivkovic, B., Morselli, P.L., Bartholini, G. (1990). The psychopharmacology of GABA synapses: update 1989. In: Youdim, M.B.H., Tipton, K.F. (eds) Neurotransmitter Actions and Interactions. Journal of Neural Transmission, vol 29. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9050-0_3

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  • DOI: https://doi.org/10.1007/978-3-7091-9050-0_3

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