Psychomotor investigations in depressed patients by comparison with Parkinson patients

  • G. Laux
  • W. Kuhn
  • W. Classen
Conference paper
Part of the Key Topics in Brain Research book series (KEYTOPICS)


Patients with major depressive disorders show impairments of cognitive abilities and motor performance. Patients with Parkinson’s disease (PD) also have slower reaction and movement times. Clinically, differential diagnosis between inhibited depression (D) and PD can be difficult. So, psychomotor functions of patients with D, PD and PD + D have been tested using the “Motorische Leistungs-Serie” (MLS) as objective assessment. Standard values of MLS in D were clearly higher than in PD. Furthermore, scores of PD + D were lower than those for PD (without depression). Under treatment an overall improvement of MLS performance in PD and PD + D (except Tapping) as well as in D (except Tapping and parts of line tracing) could be observed. Psychomotor slowing in D can be explained by central motivational deficits. Terminology of bradyphrenia as well as dopaminergic and/or noradrenergic dysfunctions being the possible neurochemical basis of this cognitive deficits are discussed.


Depressed Patient Major Depressive Disorder Simple Reaction Time Parkinson Patient Psychomotor Function 
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Copyright information

© Springer-Verlag/Wien 1989

Authors and Affiliations

  • G. Laux
    • 1
  • W. Kuhn
    • 2
  • W. Classen
    • 1
  1. 1.Departments of PsychiatryUniversity of WürzburgFederal Republic of Germany
  2. 2.Departments of NeurologyUniversity of WürzburgFederal Republic of Germany

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