Autonomic nervous system screening in patients with early Parkinson’s disease

  • A. D. Korczyn
Part of the Key Topics in Brain Research book series (KEYTOPICS)


Clinical autonomic dysfunction is rarely a problem in the initial presentation of patients with Parkinson’s disease, with the notable exception of constipation. Rather, the existence of definite and conspicuous manifestations should be an important indication that the underlying disease producing the extrapyramidal features is multi-system atrophy rather than Parkinson’s disease. The frequent occurrence of constipation may be suggestive of Parkinson’s disease, but a more detailed analysis as to the underlying mechanisms and characteristics which may possibly distinguish this from the common constipation of old age remain to be established. Furthermore, it will be of importance to look systematically for Lewy bodies in autonomic ganglia since these peripheral structures may provide tissue diagnosis, so much desired in this disease.


Orthostatic Hypotension Ergot Alkaloid Optic Nerve Disease Extrapyramidal Feature Autonomic Manifestation 
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Copyright information

© Springer-Verlag/Wien 1989

Authors and Affiliations

  • A. D. Korczyn
    • 1
  1. 1.Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael

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