Subcutaneous apomorphine in Parkinson’s disease
Motor function in patients who are disabled by parkinsonian on-off oscillations can be significantly improved by administration of subcutaneous apomorphine by diurnal infusion or intermittent injection. In conjunction with use of the peripherally acting dopamine receptor antagonist domperidone, this treatment is well tolerated and has produced prolonged benefit in patients suffering from the most intractable complication of prolonged L-dopa therapy.
KeywordsMotor Response Dopamine Receptor Agonist Intermittent Injection Dyskinetic Movement Subcutaneous Apomorphine
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