Sensory and musculo-skeletal dysfunction in Parkinson’s disease—premonitory and permanent
In Parkinson’s disease the impressive motor symptomatology has sidetracked attention from other important constituents, like those pertaining to psycho-mental, autonomous and sensory systems. Pain and dysesthesias are present in about 60% of parkinsonians and predate the overt disease in about 20%.
Predominantly of neurogenic, “primary” origin they express a disorderly processing along central sensory pathways, a defective activity of dopaminergic and other transmitter-mediator systems.
Changes affecting musculo-skelettal structures contribute a somatic, “secondary” contingent of sensory discomfort and may determine the outward appearance of the patient.
KeywordsEssential Tremor Sensory Symptom Sensory Complaint Sensory Discomfort Basal Ganglion Motor
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