Chemical modulation of membrane-bound receptors
Neurotransmitter receptor binding depends on membrane anisotropy. Endogenous processes such as ageing and exogenous factors such as neuro-toxins or drugs can affect membrane anisotropy and receptor binding as shown for dopamine (DA) and serotonin (5-HT) receptors. In M. Parkinson membrane effects have to be considered for the pathogenesis as well as for the treatment of this disease.
KeywordsMembrane Fluidity Crude Membrane Endogenous Process Toluene Exposure Striatal Membrane
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