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Chemical modulation of membrane-bound receptors

  • W. Wesemann
  • N. Weiner
  • H.-O. Lausch
  • H.-D. Mennel
Conference paper
Part of the Key Topics in Brain Research book series (KEYTOPICS)

Summary

Neurotransmitter receptor binding depends on membrane anisotropy. Endogenous processes such as ageing and exogenous factors such as neuro-toxins or drugs can affect membrane anisotropy and receptor binding as shown for dopamine (DA) and serotonin (5-HT) receptors. In M. Parkinson membrane effects have to be considered for the pathogenesis as well as for the treatment of this disease.

Keywords

Membrane Fluidity Crude Membrane Endogenous Process Toluene Exposure Striatal Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag/Wien 1989

Authors and Affiliations

  • W. Wesemann
    • 1
  • N. Weiner
    • 1
  • H.-O. Lausch
    • 1
  • H.-D. Mennel
    • 2
  1. 1.Department of NeurochemistryInstitute of Physiological ChemistryMarburg/L.Federal Republic of Germany
  2. 2.Department of Neuropathology, Institute of PathologyPhilipps-UniversityMarburg/L.Federal Republic of Germany

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