Importance of dopaminergic and GABAergic neurones of the nucleus accumbens and the caudate nucleus for motoricity

  • K. Kuschinsky
  • U. Havemann
Conference paper
Part of the Key Topics in Brain Research book series (KEYTOPICS)


In the present brief review, the pharmacological induction of akinesia and muscular rigidity in an animal model (rats) is discussed. Methods measuring these symptoms are described and the possible role played by GABAergic mechanisms in efferent pathways of the basal ganglia is discussed.


Nucleus Accumbens Superior Colliculus GABAergic Neurone Relay Station Efferent Pathway 
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Copyright information

© Springer-Verlag/Wien 1989

Authors and Affiliations

  • K. Kuschinsky
    • 1
  • U. Havemann
    • 2
  1. 1.Institute for Pharmacology and Toxicology, Faculty of PharmacyUniversity of MarburgMarburgFederal Republic of Germany
  2. 2.Max Planck-Institute for Experimental MedicineGöttingenFederal Republic of Germany

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