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N-Hydroxyamino Acids and Their Derivatives

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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

Abstract

N-Hydroxyamino acids should, at present, be treated as a new, separate, characteristic group of amino acids. This is necessitated by the particular biological action of these compounds and their derivatives. Although α-N-hydroxyamino acids were first discovered by Miller and Plöchl (1) as early as 1893, they have aroused particular interest mainly in the last twenty years.

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Abbreviations

DCCI:

dicyclohexylcarbodiimide

EEDQ:

1-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

DEAD:

diethyl azodicarboxylate

MPP:

monoperphtalic acid

TFA:

trifluoroacetic acid

TEA:

triethylamine

Py:

pyridine

Z:

benzyloxycarbonyl

trOC:

trichloroethoxycarbonyl

Su:

succinimidyl

PNP:

p-nitrophenyl

Pr:

propyl

Bu:

butyl

He:

hexyl

Ph:

phenyl

Bzl:

benzyl

p-HO-Bzl:

p-hydroxybenzyl and other acc. IUPAC rules.

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Authors and Affiliations

  1. Department of Organic Chemistry, Technical University, Gdańsk, Poland

    Andrzej Chimiak & Maria J. Milewska

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  1. Andrzej Chimiak
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  2. Maria J. Milewska
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Editors and Affiliations

  1. Department of Chemistry, The Florida State University, Tallahassee, Florida, USA

    W. Herz (Professor of Chemistry) (Professor of Chemistry)

  2. Biologisches Institut II, Lehrstuhl für Biochemie der Pflanzen, Albert-Ludwigs-Universität, Freiburg i. Br., Federal Republic of Germany

    H. Grisebach

  3. Chemistry Department, The University, Glasgow, Scotland

    G. W. Kirby Sc. D. (Regius Professor of Chemistry) (Regius Professor of Chemistry)

  4. Institut für Organische Chemie der Universität Basel, Basel, Switzerland

    Ch. Tamm

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Chimiak, A., Milewska, M.J. (1988). N-Hydroxyamino Acids and Their Derivatives. In: Herz, W., Grisebach, H., Kirby, G.W., Tamm, C. (eds) Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products. Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, vol 53. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8987-0_3

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  • DOI: https://doi.org/10.1007/978-3-7091-8987-0_3

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