Psychiatric side effects during the treatment of Parkinson’s disease

  • H. L. Klawans
Part of the Journal of Neural Transmission book series (NEURAL SUPPL, volume 27)


Dopaminergic agents including both levodopa and direct-acting agonists induce a variety psychiatric side-effects of which psychosis is the most significant. When this occurs early in the course of treatment, there is usually a history of prior psychotic illness. Chronic treatment can, however, elicit psychosis in individuals without such a history. The possible pathogenesis of this is reviewed.


Parkinsonian Patient Sleep Disruption Levodopa Therapy Sleep Complaint Formal Thought Disorder 
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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • H. L. Klawans
    • 1
  1. 1.Department of Neurological SciencesRush-Presbyterian St. Luke’s Medical CenterChicagoUSA

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