Abstract
Intrathecal injection of chymopapain causes fatal hemorrhage in rabbits and dogs [12]. To prevent the possibility of chymopapain leaking into the subarachnoid space, chemonucleolysis should not be performed immediately after myelography in order to allow any dural leak to seal [12]. McCulloch recommends a minimum delay of 24 hours [12]. We agree with other practitioners and require at least seven days between myelography and enzyme injection [1].
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© 1988 Springer-Verlag/Wien
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Laredo, JD., Busson, J., Wybier, M., Bard, M. (1988). Technique of lumbar chemonucleolysis. In: Bard, M., Laredo, JD. (eds) Interventional Radiology in Bone and Joint. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8948-1_5
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DOI: https://doi.org/10.1007/978-3-7091-8948-1_5
Publisher Name: Springer, Vienna
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