Anesthesia and complications in chymopapain chemonucleolysis

  • Marie-Christine des Essarts


Chemonucleolysis is a painful procedure which requires anesthesia. In addition, chymopapain, an enzymatic substance extracted from the latex of the unripe papaya, is antigenic. In approximately 0.5% of cases, chymopapain chemonucleolysis (CN) produces anaphylactic shock. For these reasons, CN requires the presence of an anesthesiologist experienced in radiologic procedures and capable of intervening in case of anaphylactic shock [1, 4, 12].


Mast Cell Histamine Release Tranexamic Acid Anaphylactic Reaction Anaphylactic Shock 
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Copyright information

© Springer-Verlag/Wien 1988

Authors and Affiliations

  • Marie-Christine des Essarts
    • 1
  1. 1.Department of AnesthesiaHôpital LariboisièreParisFrance

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