Pathophysiological Background for Gestational Diabetes
In normal pregnancy, glucose homeostasis is changed in the direction of diabetes. Thus, glucose tolerance gradually deteriorates (Lind et al, 1973; Kühl, 1975; Hornnes and Kühl, 1984), for which reason pregnancy is often called“diabetogenic”. In most women glucose tolerance stays within the normal range (Lind et al., 1973), but in about 1% of all pregnancies it deteriorates sufficiently for the diagnostic criteria of diabetes mel-litus to be fulfilled. This condition is termed “gestational diabetes mellitus” (Kühl, 1977).
KeywordsGestational Diabetes Mellitus Gestational Diabetic Insulin Response Late Pregnancy Insulin Binding
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