Oral Contraceptives in Women with Previous Gestational Diabetes: Influence on Glucose Metabolism
One of the earliest described metabolic effects following intake of oral contraceptives was that upon glucose tolerance (Waine etal., 1963; Wynn, 1966). Today a considerable amount of evidence substantiates that traditional brands of oral contraceptives with 50 ug estrogen or more and high pro-gestational content decrease glucose tolerance and cause a rise in plasma insulin levels (Kalkhoff, 1975; Spellacy, 1976). Despite these findings no increased risk of developing clinical diabetes has been found in epidemiological studies (Wingrave etal., 1979).
KeywordsGlucose Tolerance Oral Contraceptive Gestational Diabetes Mellitus Oral Glucose Tolerance Test Ethinyl Estradiol
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