The Use of Prophylactic Insulin in Women with Gestational Diabetes

  • D. R. Coustan


Between 1 and 5% of pregnant women develop a disturbance of carbohydrate metabolism known as gestational diabetes (Carpenter and Coustan, 1986). This abnormality is pathophysiologically similar to type II diabetes in that its main feature is insulin resistance, presumably induced by the contrainsulin hormones of pregnancy, and possibly also by placental insulin degradation. In addition, many investigators have also reported that women with gestational diabetes manifest a reduced insulin response to a glucose load when compared with normal pregnant subjects (Blohme etal., 1980; Freinkel etal., 1985; Kühl etal., 1985).


Gestational Diabetes Operative Delivery Regular Human Insulin Shoulder Dystocia Birth Trauma 
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Copyright information

© Springer-Verlag/Wien 1988

Authors and Affiliations

  • D. R. Coustan
    • 1
  1. 1.Brown University Program in MedicineProvidenceUSA

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