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The Condylocarpine Group of Indole Alkaloids

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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

Abstract

In this review we consider 24 alkaloids having the precondylocarpinetype pentacyclic skeleton and a two-carbon unit (carbons 18 and 19 in the “biogenetic numbering” of Le Men and Taylor (1)). All can be derived from precondylocarpine (1) via condylocarpine (2). To date, no comprehensive review of these alkaloids has appeared. However, considerable information can be found in M Hesse’s (2) Tables of Indole Alkaloids under the aspidospermatine-type alkaloids. Husson (3) has recently reviewed Strychnos alkaloids discovered or studied in the seventies and up to 1982. Besides the chemical and structural properties he notes plant sources of condylocarpine derivatives. Van Beek et al. (4) have listed the alkaloids isolated from the genus Tabernaemontana.

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  1. Laboratory for Organic and Bioorganic Chemistry, Department of Chemistry, Technical University of Helsinki, Finland

    M. Lounasmaa & P. Somersalo

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Editors and Affiliations

  1. Department of Chemistry, The Florida State University, Tallahassee, Florida, USA

    W. Herz (Professor of Chemistry) (Professor of Chemistry)

  2. Biologisches Institut II, Lehrstuhl für Biochemie der Pflanzen, Albert-Ludwigs-Universität, Freiburg i. Br., Federal Republic of Germany

    H. Grisebach

  3. Chemistry Department, The University, Glasgow, Scotland

    G. W. Kirby Sc. D. (Regius Professor of Chemistry) (Regius Professor of Chemistry)

  4. Institut für Organische Chemie, Universität Basel, Basel, Switzerland

    Ch. Tamm

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Lounasmaa, M., Somersalo, P. (1986). The Condylocarpine Group of Indole Alkaloids. In: Herz, W., Grisebach, H., Kirby, G.W., Tamm, C. (eds) Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products. Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, vol 50. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8888-0_2

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