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Principles of Chemotherapy in Brain Neoplasia

  • Chapter
Therapy of Malignant Brain Tumors

Abstract

For the neurooncologic clinician, brain tumors, be they primary or secondary, are a frustrating challenge. Successful therapy often is not achieved with surgery or radiation therapy. One is therefore faced with the choice of chemotherapy, itself currently a less than adequate answer. Also, for the neuroclinician, such a choice is at once intimidating. It is the purpose, then, of this chapter to put brain tumor chemotherapy into clinical perspective, beginning first with the basic principles of anticancer drug therapy, continuing through an organized schema of the currently available chemotherapeutic agents as applicable to neurooncology and applying these to the specific features of brain tumors. The focus is to work through various research angles to distill the clinically relevant perspectives of this vast subject.

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  1. Department of Neurosurgery, The Oregon Health Sciences University, Portland, OR, USA

    Prof. Dr. Mary K. Gumerlock & E. A. Neuwelt

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  1. Prof. Dr. Mary K. Gumerlock
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  1. Ludwig Boltzmann Institute of Clinical Neurobiology, Lainz Hospital, Vienna, Austria

    Kurt Jellinger

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Gumerlock, M.K., Neuwelt, E.A. (1987). Principles of Chemotherapy in Brain Neoplasia. In: Jellinger, K. (eds) Therapy of Malignant Brain Tumors. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8876-7_6

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