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Bluttransfusion und Zytomegalievirus-(CMV-)Infektion

  • P. Höcker
  • S. Panzer
  • R. Grümayer
  • U. Michl
  • W. Emminger
  • A. Wagner

Zusammenfassung

Obwohl man bereits in den fünfziger Jahren eine Übertragung von CMV durch Bluttransfusion vermutete, wurde die Bestätigung erst 1966 durch Kääriäinen erbracht, der serologisch durch den Nachweis des Anstiegs des CMV-Antikörpertiter bei Patienten mit Operation am offenen Herzen eine Übertragung von CMV durch Bluttransfusionen nachweisen konnte [25]. Dieses, als Posttransfusionssyndrom bezeichnete Zustandsbild, das gewisse Parallelen zur infektiösen Mononucleose mit einer Zunahme monozytärer Zellen und kurzfristigem Fieberanstieg aufwies, führte in seltenen Fällen auch zu Organmanifestation einer CMV-Erkrankung [7, 22, 26, 35, 37]. In den darauffolgenden Jahren wurden zahlreiche Studien durchgeführt, wobei gezeigt werden konnte, daß es vor allem bei Patienten mit häufigen Transfusionen zum Auftreten eines Posttransfusionssyndroms kommen kann [7, 15, 18, 20, 21, 26, 30, 51, 52].

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Copyright information

© Springer-Verlag/Wien 1986

Authors and Affiliations

  • P. Höcker
    • 1
  • S. Panzer
  • R. Grümayer
  • U. Michl
  • W. Emminger
  • A. Wagner
  1. 1.Intensiv-BlutbankAllgemeines KrankenhausWienÖsterreich

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