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Bluttransfusion und Immunsystem pp 48–60Cite as

Bluttransfusion und Zytomegalievirus-(CMV-)Infektion

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Zusammenfassung

Obwohl man bereits in den fünfziger Jahren eine Übertragung von CMV durch Bluttransfusion vermutete, wurde die Bestätigung erst 1966 durch Kääriäinen erbracht, der serologisch durch den Nachweis des Anstiegs des CMV-Antikörpertiter bei Patienten mit Operation am offenen Herzen eine Übertragung von CMV durch Bluttransfusionen nachweisen konnte [25]. Dieses, als Posttransfusionssyndrom bezeichnete Zustandsbild, das gewisse Parallelen zur infektiösen Mononucleose mit einer Zunahme monozytärer Zellen und kurzfristigem Fieberanstieg aufwies, führte in seltenen Fällen auch zu Organmanifestation einer CMV-Erkrankung [7, 22, 26, 35, 37]. In den darauffolgenden Jahren wurden zahlreiche Studien durchgeführt, wobei gezeigt werden konnte, daß es vor allem bei Patienten mit häufigen Transfusionen zum Auftreten eines Posttransfusionssyndroms kommen kann [7, 15, 18, 20, 21, 26, 30, 51, 52].

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Authors and Affiliations

  1. Intensiv-Blutbank, Allgemeines Krankenhaus, Alser Straße 4, A-1090, Wien, Österreich

    Doz. Dr. P. Höcker

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  1. Doz. Dr. P. Höcker
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  2. S. Panzer
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  3. R. Grümayer
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  4. U. Michl
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  5. W. Emminger
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  6. A. Wagner
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Editors and Affiliations

  1. Intensiv-Blutbank, Allgemeines Krankenhaus der Stadt Wien, Wien, Österreich

    Paul Höcker

  2. Westfälische Wilhelmsuniversität Münster, Münster, Bundesrepublik Deutschland

    Norbert Müller

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© 1986 Springer-Verlag/Wien

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Höcker, P., Panzer, S., Grümayer, R., Michl, U., Emminger, W., Wagner, A. (1986). Bluttransfusion und Zytomegalievirus-(CMV-)Infektion. In: Höcker, P., Müller, N. (eds) Bluttransfusion und Immunsystem. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8875-0_5

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  • DOI: https://doi.org/10.1007/978-3-7091-8875-0_5

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-81944-9

  • Online ISBN: 978-3-7091-8875-0

  • eBook Packages: Springer Book Archive

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