The circulating erythrocyte is an example of a cell type that appears to be perfectly adapted to its specialized role as a vehicle for the transport of oxygen. An individual erythrocyte normally performs its work as a respiratory carrier for a period of three to four months, making a seemingly endless journey between the mainstream of its intravascular existence and the outreaches of the capillary tree. This efficiently functioning cell, and the hemoglobin within it that serves as its vital principle, have developed over evolutionary history as an essential link to the development of higher forms of life.
KeywordsSickle Cell Anemia Sickle Cell Globin Gene Sickle Cell Trait Sickle Cell Anemia Patient
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