The Bunyaviridae family is a large group of over 200 distinct viruses sharing morphological, biochemical and serological properties and formerly included in the now obsolete Arbovirus group. They are transmitted by arthropods and occur most frequently in tropical countries. Many of them may cause lethal encephalitis in man and other mammals. Like many other viruses, including togaviruses, they replicate in insects without causing disease. The family has been subdivided in four genera: Bunyavirus, Nairovirus, Phlebovirus, and Uukuvirus. Clear differences between genera have been reported, such as genetic Organization, NC shape, ability to shut off host protein synthesis, glycoprotein spike arrangement, etc. Mature virions have a spherical or slightly oval shape and are 80 to 110 nm in diameter (Holmes, 1971) with a central core formed by a helical NC (von Bonsdorff et al, 1969).
KeywordsNonstructural Protein Hexagonal Array Virus Release Virus Component Segment Code
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