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Assembly of Rhabdoviridae

  • Monique Dubois-Dalcq
  • Kathryn V. Holmes
  • Bernard Rentier

Abstract

Rhabdoviruses are widely distributed among vertebrates and are also found in invertebrates and plants. They are grouped in two genera, the Lyssavirus and the Vesiculovirus. The prototype Vesiculovirus is vesicular Stomatitis virus (VSV), of which various strains have been isolated from cattle and horses as well as flies and mosquitoes (Brown and Crick, 1979). VSV produces a vesicular exanthem in bovine species and therefore is of great economic importance. The prototype of Lyssavirus is rabies virus, which can fatally infect all warm-blooded animals. Rhabdoviruses contain a bullet-shaped nucleocapsid and are bacilliform when released (Murphy and Harrison, 1979). Virion length varies from 160 and 170 nm and diameter is about 70 nm. The virus envelope is covered with surface projections (spikes) and surrounds a tightly coiled nucleocapsid (NC) containing the virus genome.

Keywords

Vesicular Stomatitis Virus Virus Component Defective Interfere Particle Monocistronic mRNAs Fine Granular Material 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 1984

Authors and Affiliations

  • Monique Dubois-Dalcq
    • 1
  • Kathryn V. Holmes
    • 2
  • Bernard Rentier
    • 3
  1. 1.Neural and Molecular Ultrastructure, Laboratory of Molecular Genetics, National Institute of Neurological and Communicative Disorders and StrokeNational Institutes of HealthBethesdaUSA
  2. 2.Department of Pathology, Uniformed ServicesUniversity of the Health SciencesBethesdaUSA
  3. 3.Laboratory of General and Medical MicrobiologyUniversity of LiegeBelgium

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