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Maturation of Preribosomes

  • Asen A. Hadjiolov
Part of the Cell Biology Monographs book series (CELLBIOL, volume 12)

Abstract

Preribosomes may be defined as discrete, free ribonucleoprotein particles containing pre-rRNA. The assembly of preribosomes starts during transcription of rRNA genes and the growing pre-rRNA chain is already coated with ribosomal and non-ribosomal proteins. The selective interaction of individual r-proteins with the respective segments in pre-rRNA clearly shows (Chooi and Leiby 1981) that its protein coating involves specific protein-RNA and protein-protein interactions. Thus, assembly of preribosomes takes place simultaneously with transcription to release upon termination an already defined particle which may be designated as the primary preribosome (containing primary pre-rRNA).

Keywords

Ribosome Biogenesis Lower Eukaryote rRNA Molecule rRNA Species Ribosomal Particle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 1985

Authors and Affiliations

  • Asen A. Hadjiolov
    • 1
  1. 1.Department of Molecular Genetics, Institute of Molecular BiologyBulgarian Academy of SciencesSofiaBulgaria

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