Indication and Results of Stereotactic Curietherapy with Iridium-192 and Iodine-125 for Non-resectable Tumours of the Hypothalamic Region

  • F. Mundinger
  • K. Weigel
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 33)


Therapeutic approaches to tumours of the hypothalamic region vary primarily depending on the degree to which the tumour can be surgically resected. However, residual portions of the tumour following surgery or recurrent tumours present special problems. In the case of hypothalamic gliomas, severe clinical deficits, significant postoperative neurologic morbidity and mortality are expected after attempts at open resection. Therefore at many institutions nothing is done after the clinical or CT diagnosis of a hypothalamic process, or at most, “ut aliquid fiat”, external irradiation might be carried out. Today this mode of procedure is highly unsatisfying and the Situation calls for an effective therapy concept. Knowledge of the type of tumour and its grading is prerequisite for selecting the therapeutic procedure. CT- stereotactic biopsy is the most reliable and least dangerous method of obtaining this information1,4,6,7. Based on the findings from the intraoperative smear preparation, the form of therapy can be immediately decided upon. Interstitial curietherapy, for example, can be initiated right away2,5.


Pituitary Adenoma Pilocytic Astrocytoma Open Resection Stereotactic Biopsy Hypothalamic Region 
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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • F. Mundinger
    • 1
  • K. Weigel
  1. 1.Abteilung Stereotaxie und NeuronuklearmedizinNeurochirurgische UniversitätsklinikFreiburg im BreisgauFederal Republic of Germany

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