An Animal Tumor Model for the Study of the Radiation Biology of 125I Interstitial Brachytherapy
A model for the study of the radiation biology of interstitial brachytherapy that uses the RIF-1 murine tumor implanted with removable high activity 125I sources is described. Results of experiments that studied the relative biological effectiveness of interstitial 125I sources, the effects of an hypoxic cell sensitizer, and the effects of drugs and radiation used in combination are discussed.
KeywordsRelative Biologic Effectiveness Interstitial Brachytherapy Radiation Biology Animal Tumor Model Cell Survival Assay
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