Advertisement

An Animal Tumor Model for the Study of the Radiation Biology of 125I Interstitial Brachytherapy

  • V. Da Silva
  • Ph. H. Gutin
  • M. Bernstein
  • K. Weaver
  • D. F. Deen
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 33)

Summary

A model for the study of the radiation biology of interstitial brachytherapy that uses the RIF-1 murine tumor implanted with removable high activity 125I sources is described. Results of experiments that studied the relative biological effectiveness of interstitial 125I sources, the effects of an hypoxic cell sensitizer, and the effects of drugs and radiation used in combination are discussed.

Keywords

Relative Biologic Effectiveness Interstitial Brachytherapy Radiation Biology Animal Tumor Model Cell Survival Assay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bernstein, M., Gutin, P. H., Weaver, K., Deen, D. F., Barcellos, M. H., 125I interstitial implants in the RIF-1 murine flank tumor: an animal model for brachytherapy. Radiat. Res. 91 (1982), 624—637.PubMedCrossRefGoogle Scholar
  2. 2.
    Bernstein, M., Gutin, P. H., Deen, D. F., Weaver, K., Levin, V., Barcellos, M. H., Radiosensitiziation of the RIF-1 murine flank tumor by demethylmisonidazole (Ro 059963) during interstitial brachytherapy. Int. J. Radiat. Oncol. Biol. Phys. 8 (1982), 487—490.PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • V. Da Silva
    • 1
  • Ph. H. Gutin
    • 1
    • 2
  • M. Bernstein
    • 1
  • K. Weaver
    • 2
  • D. F. Deen
    • 1
    • 2
  1. 1.Brain Tumor Research Center of the Department of Neurological SurgeryUniversity of CaliforniaSan FranciscoUSA
  2. 2.Department of Radiation Oncology, School of MedicineUniversity of CaliforniaSan FranciscoUSA

Personalised recommendations