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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products pp 235–264Cite as

Paralytic Shellfish Poisons

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Abstract

Paralytic shellfish poisons (PSP) are the toxins responsible for acute and often fatal poisonings caused by the consumption of certain shellfish. The phenomenon has been known since prehistoric times. A thorough docuinen tation of the incidents can be found in HALSTEAD’S treatise on poisonousmarine organisms (7). Saxitoxin (1) was the first toxin reeognized in toxic shellfish, but reeently a series of new toxins has been discovered in various specimens. The toxins have particular importance as pharmacological tools because of their unique action against sodium Channels in the excitable membrane. Earlier accounts of toxin research were reviewed by Schantz (2) and Shimizu (3).

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  1. Department of Pharmaeognosy and Environmental Health Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island, USA

    Y. Shimizu

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Shimizu, Y. (1984). Paralytic Shellfish Poisons. In: Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products. Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, vol 45. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8717-3_3

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