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Genetic Relatedness of Influenza Viruses (RNA and Protein)

  • Chapter
Genetics of Influenza Viruses

Abstract

The genomes of influenza A and B viruses are comprised of 8 single-stranded RNA segments of different molecular weights, while influenza C viruses contain only 7 segments (for reviews see Palese, 1977; Scholtissek, 1978, 1979a; Palese et al., 1980). This unusual structure of the influenza virus genome makes a genetic comparison of different isolates interesting, because during double infection of a host with two different strains of the same type, each RNA segment behaves like a chromosome, and free reassortment is possible, creating new strains. Thus, when comparing two strains, each pair of allelic RNA segments has to be studied separately.

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Scholtissek, C. (1983). Genetic Relatedness of Influenza Viruses (RNA and Protein). In: Palese, P., Kingsbury, D.W. (eds) Genetics of Influenza Viruses. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8706-7_4

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