Molecular Epidemiology of Influenza Virus

  • P. Palese
  • J. F. Young


Recent developments of new technologies have greatly advanced our ability to define the genetic constitution and molecular structure of viral agents, to determine similarities among strains and to identify differences in viral variants. Most important among these techniques are cloning and sequencing of nucleic acids, RNA fingerprinting, peptide mapping and antigenic analysis of proteins with monoclonal antibodies. The purpose of this review, the last in this book, is to discuss the epidemiology of influenza viruses in the context of these novel techniques. Special emphasis will be put on the evaluation of recent results and an examination of the epidemiological questions which may be answered using these molecular techniques.


Influenza Virus Molecular Epidemiology Human Influenza H2N2 Strain Human Influenza Virus 
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© Springer-Verlag/Wien 1983

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  • P. Palese
  • J. F. Young

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