The Relevance of Preliminary Denervation in Muscle Transplantation
It has long been recognized that the transfer of autogenous skeletal muscle has been associated with an inability to obtain complete functional recovery (Neuhof, 1923; Peer, 1955). Its ability to survive as an anatomical entity has been observed for a long time. More recent investigations using electrophysiological recordings have shown that the capacity of a transferred muscle to perform useful work is significantly impaired, Terzis (1978). Striated muscle survival and function following its transfer depends on our ability to maintain both adequate vascularization and innervation, to respect its original tension and to induce a “Plastic State” prior to transplantation (Hakelius, 1974–1975 a, b; Thompson, 1971 a, b, c).
KeywordsMuscle Force Facial Paralysis Denervated Muscle Free Graft Muscle Graft
Unable to display preview. Download preview PDF.
- 1.Hakelius, L.: Transplantation of free autogenous muscle in the treatment of facial paralysis. Scand. J. Plast. Rec. Surg. 8, 22–230 (1974).Google Scholar
- 5.Neuhof, H.: The transplantation of tissue. New York: Appleton. 1923.Google Scholar
- 6.Peer, L. A.: Transplantation of tissues, Chapt. V. Baltimore: Williams & Wilkins Co. 1955.Google Scholar
- 7.Romanul, F. C., Hogan, E.: Enzymatic change in denervated muscle. I. Histochemical Studies. Arch. Neurol. 13, 263–274 (1965). II. Biochemical Studies. Arch. Neurol. 13, 274–280 (1965).Google Scholar
- 9.Studitsky, A. N.: Free auto and homografts of muscle tissue in experiments on animals. Annals N. Y. Acad, of Sci. 120, 789–800 (1964).Google Scholar
- 10.Terzis, J., Sweet, R. C., Dykes, R. W., Williams, H. B.: Recovery of function in free muscle transplants using microneurovascular anastomoses. J. Hand Surg. 3, 37–59 (1978).Google Scholar
- 11.Thompson, N.: Treatment of facial paralysis by free skeletal muscle grafts. In: Transactions of the Fifth International Congress of Plastic and Reconstructive Surgery, pp. 66–82. Sydney: Butterworth. 1971a.Google Scholar