Advertisement

The Functional Recovery of Minced Muscles

  • C. Bertrand
  • L. Plaghki
  • G. Maréchal

Abstract

The regeneration of muscles minced and grafted orthotopically has been well described by Carlson (1972). Such muscles show a remarkable degree of recovery: they contract; they are supplied with vascularization and innervation within a few weeks after the surgery. They show noticeable morphological, biochemical and mechanical differences in comparison to normal muscles (Carlson and Gutmann, 1972; Galucci et al, 1966; Plaghki and Maréchal, 1976; Plaghki et al, 1980a, b; Rifenbericket al, 1974; Salafsky, 1971; Snow, 1973). Their functional value may be questioned, as there is no available information concerning their use by the animals. This work describes some clinical aspects of the recovery of minced triceps surae of the rat, and establish a correlation with the mechanical recovery of the regenerating muscles.

Keywords

Functional Recovery Regenerate Muscle Isometric Force Biceps Femoris Normal Muscle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Carlson, B. M.: The Regeneration of Minced Muscles (Monographs in Developmental Biology, Vol. 4). Basel: Karger. 1972.Google Scholar
  2. 2.
    Carlson, B. M., Gutmann, E.: Development of contractile properties of minced muscles regenerates in the rat. Exp. Neurol. 36, 239–249 (1972).PubMedCrossRefGoogle Scholar
  3. 3.
    Gallucci, V., Novello, F., Margreth, A., Aloisi, A.: Biochemical correlates of discontinuous muscle regeneration in the rat. Brit. J. Exp. Path. 47, 215–226 (1966).Google Scholar
  4. 4.
    Maréchal, G., Plaghki, L.: The deficit of the isometric tetanic tension redeveloped after a release of frog muscle at a constant velocity. J. gen. Physiol. 73, 453–467 (1979).PubMedCrossRefGoogle Scholar
  5. 5.
    Plaghki, L., Maréchal, G.: Time course of regeneration of minced frog muscles estimated by the level of energetic substrates. Pflüg. Arch. 361, 135–143 (1976).CrossRefGoogle Scholar
  6. 6.
    Plaghki, L., Beckers-Bleukx, G., Bertrand, C., Maréchal, G.: Creatine and actin in regenerating rat gastrocnemius muscles, in: Energetics and Gas Exchange in Exercise Physiology (Cerretelli, P., Whipp, B. J., eds.). Amsterdam: Elsevier. 1980a.Google Scholar
  7. 7.
    Plaghki, L., Colson-Van Schoor, M., Beckers-Bleukx, G., Maréchal, G.: Creatine creatinekinase and glycolytic enzymes in regenerating muscles, in: Mechanism of Muscle Adaptation to Functional Requirement (Cuba, F., Maréchal, G., Takacs, Ö., eds.). Acad. Sci. Hung. 1980b.Google Scholar
  8. 8.
    Rifenberick, D. H., Koski, C. L., Max, S. R.: Metabolic studies of skeletal muscle regeneration. Exptl. Neurology 45, 527–540 (1974).CrossRefGoogle Scholar
  9. 9.
    Salafsky, B.: Functional studies of regenerated muscle from normal and dystrophic mice. Nature (Lond.) 229, 270–272 (1971).CrossRefGoogle Scholar
  10. 10.
    Schwartz, N. B.: Changing size composition and contraction strength of gastrocnemius muscle. Am. J. Physiol. 201, 164–170 (1961).PubMedGoogle Scholar
  11. 11.
    Snow, M. H.: Metabolic activity during the degenerative and early regenerated stages of minced skeletal muscle. Anat. Rec. 176, 185–204 (1973).PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag/Wien 1981

Authors and Affiliations

  • C. Bertrand
    • 1
  • L. Plaghki
    • 1
  • G. Maréchal
    • 1
    • 2
  1. 1.Laboratoire de Physiologie GénéraleUniversité Catholique de LouvainBrusselsBelgium
  2. 2.Laboratoire de Physiologie GénéraleUCL-5540BruxellesBelgium

Personalised recommendations