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Muscle Transplantation pp 3–18Cite as

The Biology of Muscle Transplantation

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Abstract

After a long history of unsuccessful attempts, the free grafting of entire mammahan muscles has been accomphshed in both the research laboratory (Bosova, 1962; Studitsky, 1963, 1977; Carlson, 1978) and in clinical practice (Thompson, 1971). Although working completely independently of one another, Thompson and Studitsky devised similar grafting techniques. After considerable experience with various regeneration models, Studitsky (1963) elaborated the concept of the “plastic state”, a condition to which mammalian muscle must be reduced in order for massive amounts of regeneration to occur. Treatments leading to the plastic state are denervation or slicing trauma prior to whole muscle grafting, or mincing a fresh muscle into small (one mm3) fragments. According to Studitsky, the plastic state facilitates regeneration, which he considered to be the basis for the success of muscle grafts.

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References

  • Bader, D.: Reinnervation of motor endplate-containing and motor endplate-less muscle grafts. Devel. Biol. 77, 315–327 (1980).

    Article  CAS  Google Scholar 

  • Bosova, N. N.: Free autoplastic transplantation of whole muscles. (Russian.) Byull. Exp. Biol. Med. M 88–92 (1962).

    Google Scholar 

  • Bosova, N. N.: Restorative processes in dog muscles after free auto- and homografting. (Russian.) Byull. Exp. Biol. Med. 82, 1377–1379 (1976).

    Google Scholar 

  • Carlson, B. M.: The Regeneration of Minced Muscles. Basel: Karger. 1972.

    Google Scholar 

  • Carlson, B. M.: A quantitative study of muscle fiber survival and regeneration in normal, predenervated, and Marcaine-treated free muscle grafts in the rat. Exp. Neurol. 52, 421–432 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Carlson, B. M.: A review of muscle transplantatior in mammals. Physiol. Bohemoslov. 27, 387–400 (1978).

    PubMed  CAS  Google Scholar 

  • Carlson, B. M., Gutmann, E.: Regeneration in free grafts of normal and denervated muscles in the rat: Morphology and histochemistry. Anat. Ree. 183, 47–62 (1975a).

    Article  CAS  Google Scholar 

  • Carlson, B. M., Gutmann, E.: Regeneration in grafts of normal and denervated rat muscles. Contractile properties. Pflügers Arch. 353, 215–225 (1975b).

    Article  CAS  Google Scholar 

  • Carlson, B. M., Hnik, P., Tucek, S., Vejsada, R., Bader, D.: Comparison between standard free muscle grafts and grafts with intact nerves in the rat EDL muscle. (Abstr.) Anat. Ree. 193, 498 (1979)

    Google Scholar 

  • Carlson, B. M., Wagner, K. R., Max, S. R.: Reinnervation of rat extensor digitorum longus muscles after free grafting. Muscle & Nerve 1979, 304–307.

    Google Scholar 

  • Faulkner, J. A., Niemeyer, J. H., Maxwell, L. C., White, T. P.: Contractile properties of transplanted extensor digitorum longus muscles of cats. Am. J. Physiol. 238, C120-C126 (1979)

    Google Scholar 

  • Gutmann, E.: The denervated muscle. Prague: Publishing House of the Czechoslovak Academy of Sciences. 1962.

    Google Scholar 

  • Hakelius, L.: Free muscle and nerve grafting in the face, in: Reanimation of the Paralyzed Face (Rubin, L., ed.), pp. 279–293. St. Louis: Mosby. 1977.

    Google Scholar 

  • Hakelius, L., Nystrom, B.: Histochemical studies of end-plate formation in free autologous muscle transplants in cats. Scand. J. Plast. Reconstr. Surg. 9, 9–14 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Hakelius, L., Nystrom, B., Stalberg, E.: Histochemical and electrophysiological studies of autotransplanted cat muscle. Scand. J. Plast. Reconstr. Surg. 9, 15–24 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Hansen-Smith, F. M., Carlson, B. M., Irwin, K. L.: Revascularization of the freely grafted extensor digitorum longus muscle in the rat. Am. J. Anat. 158, 65–82 (1980).

    Article  PubMed  CAS  Google Scholar 

  • Holle, J.: Die muskuläre Neurotisation in der rekonstruktiven Chirurgie. Wien. klin. Wschr. 88, Suppl. 48, 1–21 (1976).

    Google Scholar 

  • Jones, P. H.: Implantation of cultured regenerate muscle cells into adult rat muscle. Exp. Neurol. 66, 602–610 (1979).

    Article  PubMed  CAS  Google Scholar 

  • Lipton, B. H., Schultz, E.: Developmental fate of skeletal muscle satellite cells. Science 205, 1292–1294 (1979).

    Article  PubMed  CAS  Google Scholar 

  • Markley, J. M., Faulkner, J. A.: Transplanted skeletal muscle regeneration in primates, with clinical correlation. In: Proceedings of the Fourth International Facial Nerve Symposium, Los Angeles, 1980. New York: Raven Press. In press.

    Google Scholar 

  • Marshall, L. M., Sanes, J. R., McMahan, U. J.: Reinnervation of original synaptic sites on muscle fiber basement membrane after disruption of muscle cells. Proc. Nat. Acad. Sci. USA 74, 3073–3077 (1977).

    Article  PubMed  CAS  Google Scholar 

  • Ontell, M.: Effects of denervation on satellite cell population of rat striated muscle. Anat. Ree. 178, 211–228 (1974).

    Article  CAS  Google Scholar 

  • Rogers, S. L., Carlson, B. M.: A quantitative assessment of muscle spindle formation in reinnervated and non-reinnervated grafts of the rat extensor digitorum longus muscle. Neuroscience (in press).

    Google Scholar 

  • Romanul, F. C. A., Hogan, E. L.: Enzymatic changes in denervated muscle. L Histochemical studies. Arch. Neurol. 12, 263–273 (1965).

    Article  Google Scholar 

  • Sanes, J. R., Hall, Z. W.: Antibodies that bind specifically to synaptic sites on muscle fiber basal lamina. J. Cell Biol. 83, 357–370 (1979).

    Article  PubMed  CAS  Google Scholar 

  • Sanes, J. R., Marshall, L. M., McMahan, U. J.: Reinnervation of muscle fiber basal lamina after removal of myofibers. J. Cell Biol. 78, 176–198 (1978).

    Article  PubMed  CAS  Google Scholar 

  • Snow, M. H.: Myogenic cell formation in regenerating rat skeletal muscle injured by mincing. II. An autoradiographic study. Anat. Ree. 188, 201–218 (1977).

    Article  CAS  Google Scholar 

  • Studitsky, A. N.: Dynamics of the development of myogenic tissue under conditions of explanation and transplantation, in: Cinemicrography in Cell Biology (Rose, G. G., ed.), pp. 171–200. New York: Academic Press. 1963.

    Google Scholar 

  • Studitsky, A. N.: The Transplantation of Muscles in Animals. (Russian.) Moscow: Izd. Meditsina. 1977.

    Google Scholar 

  • Thompson, N.: Autogenous free grafts of skeletal muscle. Plast. Reconstr. Surg. 48, 11–27 (1971).

    Article  PubMed  CAS  Google Scholar 

  • White, T. P., Sosin, D. M., Maxwell, L. C., Faulkner, J. A.: Blood flow of autotransplanted extensor digitorum longus muscles of cats. Am. J. Physiol.: Heart and Circ. Physiol, (in press).

    Google Scholar 

  • Zelena, J.: The morphogenetic influence of innervation on the ontogenetic development of muscle spindles. J. Embryol. Exp. Morphol. 5, 283–292 (1957).

    Google Scholar 

  • Zelena, J., Sobotkova, J.: Absence of muscle spindles in regenerated muscles of the rat. Physiol. Bohemoslov. 20, 433–439 (1971).

    PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Anatomy, 4622 Medical Sciences II, University of Michigan, Ann Arbor, MI, 48109, USA

    Dr. B. M. Carlson

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  1. Dr. B. M. Carlson
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Editors and Affiliations

  1. Department of Plastic and Reconstructive Surgery, Second Surgical University Clinic of Vienna, Austria

    Gerhard Freilinger  & Jürgen Holle  & 

  2. Department of Anatomy, University of Michigan, Ann Arbor, Michigan, USA

    Bruce Martin Carlson

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© 1981 Springer-Verlag/Wien

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Carlson, B.M. (1981). The Biology of Muscle Transplantation. In: Freilinger, G., Holle, J., Carlson, B.M. (eds) Muscle Transplantation. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8618-3_1

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  • DOI: https://doi.org/10.1007/978-3-7091-8618-3_1

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-8620-6

  • Online ISBN: 978-3-7091-8618-3

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