Clinical Analysis of Akinesia
Symptoms called akinesia in movement are analysed and classified into three groups. The first is that secondary to existence of marked rigidity of muscles and the second is that due to striatal dopamine deficieney, which simply be interpreted as “lack of movement”. The third is freezing or festination in quick repetitive movement especially in gait, Speech and handwriting, for which 1-Dopa therapy has no influence. Specific difficulty in the latter condition is found in the rhythm formation of repetitive movements when repetition is over 2 Hz, which the author named “hastening phenomenon converging into 5 Hz”.
However, the neural mechanism and pathology under the third group of akinesia is still not known. In most of the parkinsonian patients, it is considered that all three groups of akinesia are mixed together with variety of grade. Careful observations on the changes of clinical pictures through the course of 1-Dopa therapy and of stereotaxic surgery provided the analysis of so-called akinesia as described.
KeywordsFlexor Muscle Parkinsonian Patient Bipolar Plate Repetitive Movement Muscular Rigidity
Unable to display preview. Download preview PDF.
- Barbeau, A.: Contributions of levodopa therapy to the neurophar- macology of akinesia. In: Parkinson’s Disease, Vol. 1 (. Siegfried, J., ed.), pp. 151–174. Bern: Huber. 1972.Google Scholar
- Hornykiewicz, O.; Biochemical and pharmacological aspects of akinesia. In: Parkinson’s Disease, Vol. 1 (Siegfried, J., ed.), pp. 127 to 149. Bern: Huber. 1972.Google Scholar
- Imai, H., Narabayashi, H.: Akinesia (Jap.). Advanc. neurol. Sci. 18, 787–794 (1974).Google Scholar
- Martin, Z.P..: The Basal Ganglia and Posture, pp. 7–19 and pp. 52 to 54.Google Scholar
- Nakamura, R., Nagasaki, H., Narabayashi, H.: Arrhythmokinesia in parkinsonism. In: Advances in Parkinsonism (Birkmayer, W., et al., eds.), pp. 258–268. Basle: Roche. 1976.Google Scholar
- Narabayashi, H., Imai, H., Yokochi, M., Hirayama, K., Nakamura, R.: Cases of pure akinesia without rigidity and tremor and with no eifect by L-dopa therapy. In: Advances in Parkinsonism (Birkmayer, W., et al., eds.), pp. 335–342. Basle: Roche. 1976.Google Scholar
- Narabayashi, H., Ohye, C.: Parkinsonian tremor and nucleus ventralis intermedius of the human thalamus. In: Progress in Clinical Neuro- physiology, Vol. 5 (Desmedt, J. E., ed.), pp. 165–172. Basel: Karger. 1978.Google Scholar
- Ohye, C., Tsukahara, N., Narabayashi, H.: Rigidity and disturbance of reciprocal innervation. Confin. neurol. 26, 24–40 (1965).Google Scholar