Retrovirus Integration, Growth Regulation and Human Cancer
A reasonable model for tumorigenesis, one whieh confers a common mode of action upon retroviruses, DNA-containing viruses, chemical carcinogens and other tumor-eliciting agents takes advantage of the essence of both the oneogene-virogene theory (Huebner and Todaro, 1969) and the proto virus hypothesis (Temin, 1971) and puts them in the context of our current state of knowledge.
KeywordsCell Gene Oncogenic Virus Rous Sarcoma Virus Proliferate Cell Clone Producer Clonal Cell
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