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Human Retroviruses

  • David R. Strayer
  • David H. Gillespie
Part of the Virology Monographs book series (VIROLOGY, volume 17)

Abstract

Several lines of evidence suggest an association between RNA tumor viruses and cancer in man (Gillespie, Saxinger and Gallo, 1975; Viola et al., 1976; Gallo and Gillespie, 1977). If the link is a causal one, the availability of the causative agent could be useful both for research and for therapy. The rare isolation of infectious type-C RNA viruses from cultured human tissues has been reported by several groups (see later). These reports have generated criticisms of two major forms: (1) If type-C RNA viruses cause human cancer, they should be regularly isolated from the neoplastic tissue and (2) the viruses could be contaminants which were inadvertently introduced into the tissue sample during the course of laboratory manipulation.

Keywords

Infectious Virus Rous Sarcoma Virus Reverse Transcriptase Activity Molecular Hybridization Uninfected Target Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 1980

Authors and Affiliations

  • David R. Strayer
    • 1
  • David H. Gillespie
    • 1
  1. 1.Hahnemann Medical College and HospitalOrlowitz Cancer InstitutePhiladelphiaUSA

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