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Evolutional Process of the Formation of Multiple Resistance Plasmids

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R-Factors: Their Properties and Possible Control

Part of the book series: Topics in Infectious Diseases ((TIDIS,volume 2))

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Abstract

Sulfanilamide(SA) and its derivatives were used in Japan since 1940 against infections with both gram-positive and gram-negative bacteria and pioneered a chemotherapy as an effective antibacterial agent. In parallel with the wide use of the drugs, the isolation frequencies of SA-resistant strains of bacteria increased and reached a maximum of 90–95% of Shigella and Staphylococcus aureus isolates being resistant to SA(1–4).

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Authors
  1. S. Mitsuhashi
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  2. H. Kawabe
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  3. T. Nagate
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  4. K. Inoue
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Editor information

Editors and Affiliations

  1. Section of Chemotherapy, Sandoz Forschungsinstitut Gesellschaft m. b. H., Brunnerstrasse 59, A-1235, Vienna, Austria

    Jürgen Drews (Head) (Head)

  2. Department of Experimental Chemotherapy, Sandoz Forschungsinstitut Ges. m. b. H., Brunnerstrasse 59, A-1235, Vienna, Austria

    Gregor Högenauer

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© 1977 Springer-Verlag/Wien

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Mitsuhashi, S., Kawabe, H., Nagate, T., Inoue, K. (1977). Evolutional Process of the Formation of Multiple Resistance Plasmids. In: Drews, J., Högenauer, G. (eds) R-Factors: Their Properties and Possible Control. Topics in Infectious Diseases, vol 2. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8501-8_11

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  • DOI: https://doi.org/10.1007/978-3-7091-8501-8_11

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-8503-2

  • Online ISBN: 978-3-7091-8501-8

  • eBook Packages: Springer Book Archive

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