Advertisement

The Relationship of Hallucinations to the Depth Structures of the Temporal Lobe

  • S. M. Weingarten
  • D. G. Cherlow
  • E. Holmgren
Part of the Acta Neurochirurgica Supplementum book series (NEUROCHIRURGICA, volume 24)

Abstract

The purpose of this paper is to present some clinical data which suggests a relationship between abnormal electrical discharges in the depth structures of the temporal lobe and hallucinations. The information has been derived from a series of patients referred to the UCLA Neuropsychiatric Institute who suffered from temporal lobe epilepsy intractable to intensive pharmacologic regimes. The patients were studied with electrodes placed bilaterally in the depth structures of the temporal lobe as well as over the calvarium to monitor the electrical activity of the brain during the ictal and inter-ictal stages. If a unilateral focus for their seizures could be found, it was surgically excised in a second procedure aimed at alleviating their convulsive disorder. One of the patients studied presented initially with a complex hallucination as part of her seizure. In reviewing our series of patients it was of interest to note that hallucinations were produced by electrical stimulation of the depth structures of the temporal lobe in certain patients. The electrical stimulations were carried out in an attempt to induce seizure activity.

Keywords

Electrical Stimulation Temporal Lobe Temporal Lobe Epilepsy Temporal Horn Depth Structure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Crandall, P. H., Walter, R. D., Rand, R. W. (1963), Clinical applications on stereotaxically implanted electrodes in temporal lobe epilepsy. J. Neurosurg. 20, 827–840.PubMedCrossRefGoogle Scholar
  2. 2.
    Delgado, J. M. R., Rosvald, H. E., Looney, E. (1956), Evoking conditioned fear by electrical stimulation of subcortical structures in the monkey brain. J. Comp. Physiol. Psydiol. 49, 373–380.CrossRefGoogle Scholar
  3. 3.
    Douglas, R. J. (1967), The hippocampus and behaviour. 67, #6, 416–442.Google Scholar
  4. 4.
    Feindell, W., Penfield, W. (1954), Localization of discharge in temporal lobe automatism. AMA Arch. Neurol. Psych. 72, 605–630.Google Scholar
  5. 5.
    Feldman, S. (1962), Neurophysiological mechanism modifying afferent hypothalamus-hippocampal conduction. Exper. Neurol. 5, 269–291.CrossRefGoogle Scholar
  6. 6.
    Higgins, J. W., Mahl, G. F., Delgado, M. J. R., Hamlin, H. (1956), Behavioural dianges during intracerebral electrical stimulation. AMA Ardb. Neurol. Psych. 76, 299–449.Google Scholar
  7. 7.
    Horowitz, M. D., Adams, J. E. (1970), Hallucination on brain stimulation: Evidences for revision of the Penfield hypothesis. In: Origin and medianisms of hallucination ( Keup, W., ed.), pp. 13–22. New York: Plenum Press.Google Scholar
  8. 8.
    Ishibashi, T., Horo, H., Endo, K., Sato, T. (1964), Hallucinations produced by electrical stimulation of temporal lobes in sdiizophrenic patients. Tohuku J. exp. Med. 82, 124–139.Google Scholar
  9. 9.
    Jasper, H. H., Rasmussen, T. (1958), Studies of clinical and electrical responses to deep temporal stimulation in man with some consideration of functional anatomy. Ass. Res. Nerv. Ment. Dis. 36, 316–334.Google Scholar
  10. 10.
    Kaada, B. R. (1952), Somatomotor autonomic and EEG responses to electrical stimulation of rhinencephalen and other structures in primates, cats and dogs. Acta Physiol. Scand. 24 (Suppl. 83), 1–263.Google Scholar
  11. 11.
    Klinger, J., Gloor, P. (1960), The connections of the amygdala and of the anterior temporal cortex in the human brain. J. Comp. Neurol. 115, 333–354.CrossRefGoogle Scholar
  12. 12.
    Kubie, L. (1953), Some implications for psydioanalytic analysis of modern concepts of the organization of the brain. Psychoanalytic Quart. 22, 21–68.Google Scholar
  13. 13.
    MacLean, P. D. (1949), Psychosomatic disease and the visceral brain. Psychosomatic Med. 11, 338–351.Google Scholar
  14. 14.
    MacLean, P. D. (1950), Developments in EEG: The basal and temporal regions. Yale J. Biol, and Med. 22, 437–451.Google Scholar
  15. 15.
    MacLean, P. D. (1952), Some psychiatric implications of physiologic studies of frontotemporal portion of limbic system. EEG and Clin. Neurophysiol. 4, 407–418.Google Scholar
  16. 16.
    MacLean, P. D., Delgado, J. M. R. (1953), Electrical and chemical stimulation of frontotemporal portion of limbic system in the walking animal. EEG and Clin. Neurophysiol. 5, 91–100.Google Scholar
  17. 17.
    Mahl, G. F., Rothenberg, A., Delgado, J. M. R., Hamlin, H. (1964), Psychological response in human to intracerebral stimulation. Psychosomatic Med. 26, 337–368.Google Scholar
  18. 18.
    Marsan, C. A., Stoll, J. (1951), Subcortical connections of temporal pole in relation to temporal lobe seizures. AMA Arch. Neurol. Psychiat. 66, 669–686.Google Scholar
  19. 19.
    Papez, J. W. (1937), A proposed mechanism of emotion. Arch. Neurol. Psychiat. 38, 725–743.Google Scholar
  20. 20.
    Penfield, W. (1952), Memory mechanism. AMA Arch. Neurol. Psychiat. 66, 669–686.Google Scholar
  21. 21.
    Penfield, W., Perot, P. (1963), The brain’s record of auditory and visual experience. Brain 86, 595–696.PubMedCrossRefGoogle Scholar
  22. 22.
    Spencer, W. A., Kandel, E. R. (1961), Hippocampal neuron response to selective actovation of recurrent collaterals of hippocampal axons. Exp. Neurol. 4, 149–161.CrossRefGoogle Scholar
  23. 23.
    Talairadi, J., David, M., Tournoux, P. (1958), L’exploration chirurgicale stereo-taxique du lobe temporal dans l’epilepsie temporale, p. 136. Paris: Masson et Cie.Google Scholar
  24. 24.
    Votow, C. L. (1960), Certain functional and anatomical relations of the cornu ammonis of the Macaque Monkey. J. Comp. Neurol. 114, 283–293.CrossRefGoogle Scholar
  25. 25.
    Whittock, D. G., Nauta, W. J. (1956), Subcortical projections from the temporal neocortex in Macaca Mulatta. J. Comp. Neurol. 106, 183–212.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • S. M. Weingarten
    • 1
  • D. G. Cherlow
  • E. Holmgren
  1. 1.Neurological SurgeryBeverly HillsUSA

Personalised recommendations