Estimation of the Neural Noise Within the Human Thalamus

  • A. Fukamachi
  • Ch. Ohye
  • Y. Saito
  • H. Narabayashi
Part of the Acta Neurochirurgica Supplementum book series (NEUROCHIRURGICA, volume 24)


We systematically studied neural noise patterns in 18 Parkinsonian patients with the aid of an amplitude averaging circuit for quantitative estimation of the neural noise level. In our anterolateral to posteromedial tracks, the following results were obtained and discussed from practical points of view.
  1. 1.

    It is demonstrated that the variation of the neural noise level along the descent of the electrode corresponds well to different subcortical structures, and is therefore reliable for identifying them precisely.

  2. 2.

    In and around the VL nucleus, there were some differences in the neural noise pattern between the medial and lateral groups. In the medial group (4 cases), upper borders of the thalamus were clearly delineated, but lower borders were not. Steep increases of the noise level were found about + 10 mm above IC-line probably corresponding to the entrance of VL nucleus and the upper half of the VL showed the highest level. On the other hand, in the lateral group (6 cases), intrathalamic noise patterns were not so characteristic as medial group and noise levels were lower. In three cases upper borders of the thalamus were not so distinct. Lower borders were, on the contrary, more clearly distinguished than the medial group.

  3. 3.

    Cases with simultaneous recordings with two electrodes in parallel with frontal section were reported. This method was proved to be useful in delineating the lateral edge of the thalamus, especially in the case with dilatation of the third ventricle.

  4. 4.

    In the Vim nucleus, high levels of the neural noise were demonstrated. Activity of kinesthetic neurons were mostly found, if any, among the higher noise levels.



Noise Level Caudate Nucleus Medial Group Simultaneous Recording Frontal Section 
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  1. Albe-Fessard, D., Arfel, G., Guiot, G. (1963), Activités électriques caractéristiques de quelques structures cérébrales diez l’homme. Ann. Chir. 17, 1185–1214.PubMedGoogle Scholar
  2. Albe-Fessard, D., Arfel, G., Guiot, G. Derome, P., Hertzog, E., Vourc’h, G., Brown, H. Aleonard, P., De La Herren, J., Trigo, J. C. (1966), Electrophysiological studies of some deep cerebral structures in man. J. Neurol. Sci. 3, 37–51.PubMedCrossRefGoogle Scholar
  3. Arduini, A., Pinneo, L. R. (1962), A method for the quantification of tonic activity in the nervous system. Arch. ital. Biol. 100, 415–424.Google Scholar
  4. Bogren, H., Wickbom, I., von Essen, C., Thulin, C. A. (1971), The width of the third ventricle in neurosurgical patients with extrapyramidal movement disorders. Confín. Neurol. (Basel) 33, 120–128.CrossRefGoogle Scholar
  5. Buchwald, J. S., Grover, F. S. (1970), Amplitudes of background fast activity characteristic of specific brain sites. J. Neurophysiol. 33, 148–159.PubMedGoogle Scholar
  6. Dewulf, A. (1971), Anatomy of the normal human thalamus, Topometry and standardized nomenclature. Amsterdam-London-New York: Elsevier Publishing Company. 1971.Google Scholar
  7. Fukamachi, A., Ohye, C., Narabayashi, H. (1973), Delineation of the thalamic nuclei with a microelectrode in stereotaxic surgery for parkinsonism and cerebral palsy. J. Neurosurg. 39, 214–225.PubMedCrossRefGoogle Scholar
  8. Goodman, S. J., Mann, P. E. G. (1967), Reticular and thalamic multiple unit activity during wakefulness, sleep and anesthesia. Exp. Neurol. 19, 11–24.PubMedCrossRefGoogle Scholar
  9. Goto, A., Kosaka, K., Kubota, K., Nakamura, R., Narabayashi, H. (1968), Thalamic potentials from muscle afferents in the human. Arch. Neurol. 19, 302–309.PubMedCrossRefGoogle Scholar
  10. Grover, F. S., Buchwald, J. S. (1970), Correlation of cell size with amplitude of background fast activity in specific brain nuclei. J. Neurophysiol. 33, 160–171.PubMedGoogle Scholar
  11. Hongell, A., Wallin, G., Hagbarth, K. E. (1973), Unit activity connected with movement initiation and arousal situations recorded from the ventrolateral nucleus of the human thalamus. Acta Neurol. Scand. 49, 681–698.Google Scholar
  12. Jasper, H., Bertrand, G. (1966), Thalamic units involved in somatic sensation and voluntary and involuntary movements in man. In: The Thalamus, pp. 365–390 ( Purpura, D. P., Yahr, M. D., eds.). New York: Columbia University Press.Google Scholar
  13. Ohye, C., Fukamai, A., Narabayashi, H. (1972), Spontaneous and evoked activity of sensory neurons and their organization in the human thalamus. 2. Neurol. 203, 219–234.CrossRefGoogle Scholar
  14. Ohye, C., Fukamadii, A., Narabayashi, H., Narabayashi, H. (1972), Activity of thalamic neurons and their receptive fields in different functional states in man. In: Neurophysiology studied in man, pp. 78–89 ( Somjen, G. G., ed.). Amsterdam: Excerpta Medica.Google Scholar
  15. Ohye, C., Fukamadii, A., Narabayashi, H., Saito, Y., Fukamachi, A., Narabayashi, H. (1974), An analysis of the spontaneous rhythmic and non-rhythmic burst discharges in the human thalamus. J. Neurol. Sci. 22, 245–259.PubMedCrossRefGoogle Scholar
  16. Podvoll, E. M., Goodman, S. J. (1967), Averaged neural electrical activity and arousal. Science 155, 223–225.PubMedCrossRefGoogle Scholar
  17. Saito, Y., Ohye, C. (1974), Automatically controlled recording and processing of thalamic unit disdiarges in human stereotaxic operation. Confin. Neurol. (Basel) 36, 314–325.CrossRefGoogle Scholar
  18. Selby, G. (1968), Cerebral atrophy in parkinsonism. J. Neurol. Sci. 6, 517–559.PubMedCrossRefGoogle Scholar
  19. Schlag, J., Balvin, R. (1963), Background activity in the cerebral cortex and reticular formation in relation with the electroencephalogram. Exp. Neurol. 8, 203–219.CrossRefGoogle Scholar
  20. Velasco, F., Molina-Negro, P. (1973), Elektrophysiological topography of the human diencephalon. J. Neurosurg. 38, 204–214.PubMedCrossRefGoogle Scholar
  21. Weber, D. S., Buchwald, J. S. (1965), A technique for recording and integrating mutiple unit activity simultaneously with the EEG in chronic animals. Electroenceph. din. NeurophysioL 19, 190–192.Google Scholar

Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • A. Fukamachi
    • 1
    • 2
  • Ch. Ohye
    • 1
  • Y. Saito
    • 1
  • H. Narabayashi
    • 1
  1. 1.Neurological Clinic for Nervous Disease and Stereotaxy NakameguroMeguro, TokyoJapan
  2. 2.Department of Neurosurgery School of MedicineGunma University3-39, Showa-Machi Maebashi, GunmaJapan

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