The Role of Focal and Extrafocal Structures in the Triggering of Epileptic Spikes: An Experimental Study

  • F. Ferrillo
  • R. Amore
  • M. Palestini
  • G. Rosadini
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 23)


Epileptic discharges from a cortical focus tend to involve other cerebral areas particularly surrounding neuropil, homotopic contralateral cortex and subcortical centres. They can also induce the development of independent epileptic foci in distant areas of the brain. In these studies the topographic distribution of extrafocal discharges and the chronology of their appearance as independent phenomena have been mainly used (Wilder 1972). On the other side, problems related to morphology and temporal relationships among discharges simultaneously recorded in different structures have been almost neglected (Tharp 1971; Mares 1973).


Caudate Nucleus Sensorimotor Cortex Epileptic Focus Epileptic Discharge Epileptogenic Focus 
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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • F. Ferrillo
    • 1
  • R. Amore
    • 1
  • M. Palestini
    • 1
    • 2
  • G. Rosadini
    • 1
  1. 1.Centre for Cerebral Neurophysiology of National Council of ResearchesInstitute of Neurophysiopathology of the UniversityGenoaItaly
  2. 2.Centro de Psiquiatria ExperimentalUniversidad de ChileSantiago de ChileChile

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