Formation of Glutamate and GABA in Epileptogenic Tissue from Human Hippocampus in Vitro

  • T. Turský
  • M. Laššánová
  • M. Šramka
  • P. Nádvorník
Conference paper
Part of the Acta Neurochirurgica book series (NEUROCHIRURGICA, volume 23)


Changes in the amino acid levels of epileptogenic foci of man were described by Van Gelder et al. (1972). Similar changes were found by Koyama (1972) during cobalt-induced epilepsy in rats. Changes of amino acid levels and of the activity of enzymes, involved in the brain amino metabolism, produced by convulsions were described by several investigators (Van Gelder 1974, Wiechert and Göllnitz 1970).


Amino Acid Level Amino Acid Metabolism Neutral Amino Acid Focal Epilepsy Glutamate Decarboxylase 
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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • T. Turský
    • 2
  • M. Laššánová
    • 1
  • M. Šramka
    • 1
  • P. Nádvorník
    • 1
  1. 1.Department of Biochemistry and Neurosurgical Clinic, Medical Faculty and Institute of BiochemistryComenius UniversityBratislavaČSSR
  2. 2.Department of Biochemistry, Medical FacultyComenius UniversityBratislavaČSSR

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