Immunization against Pseudomonas in Burn Disease
Pseudomonas aeruginosa is a ubiquitous microbe which rarely causes diseases in healthy individuals. However, in patients with depressed immunity, this organism frequently becomes pathogenic, and such infections often result in septic death (1). Patients with major thermal injury have been particularly prone to develop Pseudomonas infections because many of their host defense mechanisms are compromised, and there is an ever present portal of entry via the burn eschar which can rarely be sterilized by topical antimicrobial therapy.
KeywordsPositive Blood Culture Total Body Surface Area Hyperimmune Globulin Dent Control Septic Death
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